Cancer-Associated Cachexia
The lab investigates the metabolic and inflammatory drivers of cachexia to identify biomarkers, mechanisms, and intervention points that improve patient outcomes.
Cancer Biology · Metabolism · Immunology · Translation
Gang Huang Lab is an interdisciplinary research group at UT Health San Antonio and Mays Cancer Center spanning hematology, solid tumors, metabolism, immunology, trauma research, and product development.
UT Health San Antonio and Mays Cancer Center
142
Peer-reviewed publications
9
Lab members
4
Research programs
2
Spinout companies
Overview
At The Huang Lab, we are dedicated to advancing the understanding and treatment of human disease through rigorous, multidisciplinary research. Under the leadership of Dr. Gang Huang, our team seeks to bridge fundamental discoveries with real-world applications, with a particular emphasis on hematology, metabolism, cancer biology, medical product development, CAR T-cell therapy, trauma research, and military health.
We focus on the complexities of both blood-related cancers and solid tumors while exploring how metabolic pathways and immune responses influence disease progression. By integrating expertise across these domains, we strive to develop innovative interventions that improve patient care and outcomes worldwide.
How we work
Mechanisms of cancer, metabolism, immune dysfunction, and trauma at the bench.
Models and translational assays that pressure-test each target and technology.
Companies formed around validated technologies — like Powerhouse Therapeutics and Abioremedi.
IND-enabling studies, manufacturing, capital, and partnerships that carry products to market.
Therapies reaching patients — in clinics, trauma care, and the field.
Research
The lab investigates the metabolic and inflammatory drivers of cachexia to identify biomarkers, mechanisms, and intervention points that improve patient outcomes.
The lab studies MDS, MPN, acute leukemia, and blood disorders by connecting stem cell regulation with mitochondrial metabolism and epigenetic control.
The lab builds next-generation immunotherapies for solid tumors, with emphasis on liver cancer, CAR T-cell engineering, and the tumor immune microenvironment.
The lab develops synthetic blood oxygen carriers and trauma-relevant therapeutics, working with the U.S. Army Institute of Surgical Research and Department of Defense partners.
Spin-outs
Join the lab
The lab welcomes postdoctoral scholars, graduate students, undergraduates, post-baccalaureate researchers, and staff who want to work on cancer biology, metabolism, immunology, genetics, and translational therapeutics.
Prospective trainees should fill out the application form and contact current lab members about positions.
News
Feb 25, 2026
The Huang Lab received support to advance preclinical development of PH102 for hepatocellular carcinoma, reinforcing the lab’s translational focus.
Read articleOct 1, 2025
Vincent Pham will present Huang Lab research at the 2025 San Antonio Liver Cancer Symposium.
Read articleSep 10, 2025
Dr. Gang Huang will present the lab’s latest work on PH102 at the 2025 La Frontera Symposium.
Read article