Huang Lab

Publications

Publications

Browse recent publications with filters for title, author, journal, and year.

Last updated

July 20, 2026

Showing 51–75 of 143 publications · Page 3 of 6

2019

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, Wolf ER, Ramdas B, Cai Z, Gao H, Luo N, Sun Y, Wong TN, Link DC, Liu Y, Boswell HS, Mayo LD, Huang G, Kapur R, Yoder MC, Broxmeyer HE, Gao Z, Liu Y

Nature communications · 2019 Dec 11 · PMID 31827082

View on PubMed DOI: 10.1038/s41467-019-13542-2

2019

SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints

Dong Y, Zhao X, Feng X, Zhou Y, Yan X, Zhang Y, Bu J, Zhan D, Hayashi Y, Zhang Y, Xu Z, Huang R, Wang J, Zhao T, Xiao Z, Ju Z, Andreassen PR, Wang QF, Chen W, Huang G

Leukemia · 2019 Nov · PMID 30967619

View on PubMed DOI: 10.1038/s41375-019-0456-2

2019

Deletion of a flippase subunit Tmem30a in hematopoietic cells impairs mouse fetal liver erythropoiesis

Yang F, Huang Y, Chen X, Liu L, Liao D, Zhang H, Huang G, Liu W, Zhu X, Wang W, Lobo CA, Yazdanbakhsh K, An X, Ju Z

Haematologica · 2019 Oct · PMID 30819915

View on PubMed DOI: 10.3324/haematol.2018.203992

2019

Using circulating tumor DNA to monitor myelodysplastic syndromes status

Zhao P, Qin J, Liu W, Zhu Q, Fan T, Xiao H, Wang J, Huang G, Xiaomei H

Hematological oncology · 2019 Oct · PMID 31291480

View on PubMed DOI: 10.1002/hon.2649

2019

Identification and transcriptome analysis of erythroblastic island macrophages

Li W, Wang Y, Zhao H, Zhang H, Xu Y, Wang S, Guo X, Huang Y, Zhang S, Han Y, Wu X, Rice CM, Huang G, Gallagher PG, Mendelson A, Yazdanbakhsh K, Liu J, Chen L, An X

Blood · 2019 Aug 1 · PMID 31101625

View on PubMed DOI: 10.1182/blood.2019000430

2019

Prognostic impact of red blood cell distribution width in myelodysplastic syndromes

Shi Z, Li B, Huang H, Qin T, Xu Z, Zhang H, Fang L, Pan L, Hu N, Qu S, Huang G, Gale RP, Xiao Z

British journal of haematology · 2019 Jul · PMID 30836422

View on PubMed DOI: 10.1111/bjh.15830

2019

RUNX represses Pmp22 to drive neurofibromagenesis

Hall A, Choi K, Liu W, Rose J, Zhao C, Yu Y, Na Y, Cai Y, Coover RA, Lin Y, Dombi E, Kim M, Levanon D, Groner Y, Boscolo E, Pan D, Liu PP, Lu QR, Ratner N, Huang G, Wu J

Science advances · 2019 Apr · PMID 31032403

View on PubMed DOI: 10.1126/sciadv.aau8389

2019

Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally

Huang H, Weng H, Zhou K, Wu T, Zhao BS, Sun M, Chen Z, Deng X, Xiao G, Auer F, Klemm L, Wu H, Zuo Z, Qin X, Dong Y, Zhou Y, Qin H, Tao S, Du J, Liu J, Lu Z, Yin H, Mesquita A, Yuan CL, Hu YC, Sun W, Su R, Dong L, Shen C, Li C, Qing Y, Jiang X, Wu X, Sun M, Guan JL, Qu L, Wei M, Müschen M, Huang G, He C, Yang J, Chen J

Nature · 2019 Mar · PMID 30867593

View on PubMed DOI: 10.1038/s41586-019-1016-7

2019

The high NRF2 expression confers chemotherapy resistance partly through up-regulated DUSP1 in myelodysplastic syndromes

Lin P, Ren Y, Yan X, Luo Y, Zhang H, Kesarwani M, Bu J, Zhan D, Zhou Y, Tang Y, Zhu S, Xu W, Zhou X, Mei C, Ma L, Ye L, Hu C, Azam M, Ding W, Jin J, Huang G, Tong H

Haematologica · 2019 Mar · PMID 30262569

View on PubMed DOI: 10.3324/haematol.2018.197749

2019

[Consistency Analysis of Gene Mutation Sites of Bone Marrow Tumor DNA and Circulating Tumor DNA in Patients with Myelodysplastic Syndrome]

Zhao P, Zhu QZ, Fan T, Liu WY, Xiao HY, Qin JY, Huang G, Hu XM

Zhongguo shi yan xue ye xue za zhi · 2019 Feb · PMID 30738462

View on PubMed DOI: 10.7534/j.issn.1009-2137.2019.01.024

2018

A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence

Lu B, Klingbeil O, Tarumoto Y, Somerville TDD, Huang YH, Wei Y, Wai DC, Low JKK, Milazzo JP, Wu XS, Cao Z, Yan X, Demerdash OE, Huang G, Mackay JP, Kinney JB, Shi J, Vakoc CR

Cancer cell · 2018 Dec 10 · PMID 30503706

View on PubMed DOI: 10.1016/j.ccell.2018.10.015

2018

The usefulness of mutational data on prognosis of myelodysplastic syndromes: alone or incorporated into the IPSS-R?

Li B, Liu J, Xu Z, Qin T, Shi Z, Song Z, Huang H, Fang L, Zhang H, Pan L, Hu N, Qu S, Zhang Y, Huang G, Xiao Z

British journal of haematology · 2018 Dec · PMID 29193004

View on PubMed DOI: 10.1111/bjh.15036

2018

Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes

Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger GM, Wang J, Dong Y, Zhou Y, Wang J, Wu L, Bu J, Chen A, Zhao X, Sun X, Chetal K, Olsson A, Watanabe M, Romick-Rosendale LE, Harada H, Shih LY, Tse W, Bridges JP, Caligiuri MA, Huang T, Zheng Y, Witte DP, Wang QF, Qu CK, Salomonis N, Grimes HL, Nimer SD, Xiao Z, Huang G

Cancer discovery · 2018 Nov · PMID 30139811

View on PubMed DOI: 10.1158/2159-8290.CD-17-1203

2018

Defective transcription elongation in a subset of cancers confers immunotherapy resistance

Modur V, Singh N, Mohanty V, Chung E, Muhammad B, Choi K, Chen X, Chetal K, Ratner N, Salomonis N, Weirauch MT, Waltz S, Huang G, Privette-Vinnedge L, Park JS, Janssen EM, Komurov K

Nature communications · 2018 Oct 23 · PMID 30353012

View on PubMed DOI: 10.1038/s41467-018-06810-0

2018

A novel fusion of PDGFRB to TSC1, an intrinsic suppressor of mTOR-signaling pathway, in a chronic eosinophilic leukemia patient with t(5;9)(q32;q34)

Zhang Y, Qu S, Wang Q, Li J, Xu Z, Qin T, Huang G, Xiao Z

Leukemia & lymphoma · 2018 Oct · PMID 29384404

View on PubMed DOI: 10.1080/10428194.2018.1427855

2018

Loss of YTHDF2-mediated m(6)A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration

Wang H, Zuo H, Liu J, Wen F, Gao Y, Zhu X, Liu B, Xiao F, Wang W, Huang G, Shen B, Ju Z

Cell research · 2018 Oct · PMID 30150673

View on PubMed DOI: 10.1038/s41422-018-0082-y

2018

Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation

Zhou Y, Yan X, Feng X, Bu J, Dong Y, Lin P, Hayashi Y, Huang R, Olsson A, Andreassen PR, Grimes HL, Wang QF, Cheng T, Xiao Z, Jin J, Huang G

Haematologica · 2018 Jul · PMID 29650642

View on PubMed DOI: 10.3324/haematol.2018.187708

2018

SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia

Bu J, Chen A, Yan X, He F, Dong Y, Zhou Y, He J, Zhan D, Lin P, Hayashi Y, Sun Y, Zhang Y, Xiao Z, Grimes HL, Wang QF, Huang G

Leukemia · 2018 Apr · PMID 29249820

View on PubMed DOI: 10.1038/leu.2017.339

2018

SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS

Huang Y, Hale J, Wang Y, Li W, Zhang S, Zhang J, Zhao H, Guo X, Liu J, Yan H, Yazdanbakhsh K, Huang G, Hillyer CD, Mohandas N, Chen L, Sun L, An X

Journal of hematology & oncology · 2018 Feb 12 · PMID 29433555

View on PubMed DOI: 10.1186/s13045-018-0558-8

2018

Clinical features and biological implications of different U2AF1 mutation types in myelodysplastic syndromes

Li B, Liu J, Jia Y, Wang J, Xu Z, Qin T, Shi Z, Song Z, Peng S, Huang H, Fang L, Zhang H, Pan L, Hu N, Qu S, Zhang Y, Wu J, Liu N, Ru K, Huang G, Xiao Z

Genes, chromosomes & cancer · 2018 Feb · PMID 29057546

View on PubMed DOI: 10.1002/gcc.22510

2018

Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia

Huang L, Liu D, Wang N, Ling S, Tang Y, Wu J, Hao L, Luo H, Hu X, Sheng L, Zhu L, Wang D, Luo Y, Shang Z, Xiao M, Mao X, Zhou K, Cao L, Dong L, Zheng X, Sui P, He J, Mo S, Yan J, Ao Q, Qiu L, Zhou H, Liu Q, Zhang H, Li J, Jin J, Fu L, Zhao W, Chen J, Du X, Qing G, Liu H, Liu X, Huang G, Ma D, Zhou J, Wang QF

Cell research · 2018 Feb · PMID 29148541

View on PubMed DOI: 10.1038/cr.2017.146

2018

Whole exome sequencing identifies novel mutations of epigenetic regulators in chemorefractory pediatric acute myeloid leukemia

Zhan D, Zhang Y, Xiao P, Zheng X, Ruan M, Zhang J, Chen A, Zou Y, Chen Y, Huang G, Hu S, Wang QF, Zhu X

Leukemia research · 2018 Feb · PMID 29253671

View on PubMed DOI: 10.1016/j.leukres.2017.12.001

2018

Thalidomide plus prednisone with or without danazol therapy in myelofibrosis: a retrospective analysis of incidence and durability of anemia response

Luo X, Xu Z, Li B, Qin T, Zhang P, Zhang H, Fang L, Pan L, Hu N, Qu S, Zhang Y, Huang G, Peter Gale R, Xiao Z

Blood cancer journal · 2018 Jan 15 · PMID 29335406

View on PubMed DOI: 10.1038/s41408-017-0029-4