Publications

CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells

O'Brien KB, Alberich-Jordà M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S

Development (Cambridge, England) · 2010 Jul · PMID 20530543

Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1

Kamikubo Y, Zhao L, Wunderlich M, Corpora T, Hyde RK, Paul TA, Kundu M, Garrett L, Compton S, Huang G, Wolff L, Ito Y, Bushweller J, Mulloy JC, Liu PP

Cancer cell · 2010 May 18 · PMID 20478528

The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior

Liu Y, Elf SE, Asai T, Miyata Y, Liu Y, Sashida G, Huang G, Di Giandomenico S, Koff A, Nimer SD

Cell cycle (Georgetown, Tex.) · 2009 Oct 1 · PMID 19755852

p53 regulates hematopoietic stem cell quiescence

Liu Y, Elf SE, Miyata Y, Sashida G, Liu Y, Huang G, Di Giandomenico S, Lee JM, Deblasio A, Menendez S, Antipin J, Reva B, Koff A, Nimer SD

Cell stem cell · 2009 Jan 9 · PMID 19128791

Genetic evidence of PEBP2beta-independent activation of Runx1 in the murine embryo

Yokomizo T, Yanagida M, Huang G, Osato M, Honda C, Ema M, Takahashi S, Yamamoto M, Ito Y

International journal of hematology · 2008 Sep · PMID 18594778

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

Ebralidze AK, Guibal FC, Steidl U, Zhang P, Lee S, Bartholdy B, Jorda MA, Petkova V, Rosenbauer F, Huang G, Dayaram T, Klupp J, O'Brien KB, Will B, Hoogenkamp M, Borden KL, Bonifer C, Tenen DG

Genes & development · 2008 Aug 1 · PMID 18676813

Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity

Zhao X, Jankovic V, Gural A, Huang G, Pardanani A, Menendez S, Zhang J, Dunne R, Xiao A, Erdjument-Bromage H, Allis CD, Tempst P, Nimer SD

Genes & development · 2008 Mar 1 · PMID 18316480

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis

Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG

Nature genetics · 2008 Jan · PMID 17994017

The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis

Hoogenkamp M, Krysinska H, Ingram R, Huang G, Barlow R, Clarke D, Ebralidze A, Zhang P, Tagoh H, Cockerill PN, Tenen DG, Bonifer C

Molecular and cellular biology · 2007 Nov · PMID 17785440

Potential autoregulation of transcription factor PU.1 by an upstream regulatory element

Okuno Y, Huang G, Rosenbauer F, Evans EK, Radomska HS, Iwasaki H, Akashi K, Moreau-Gachelin F, Li Y, Zhang P, Göttgens B, Tenen DG

Molecular and cellular biology · 2005 Apr · PMID 15767686

Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion 16 chimera

Huang G, Shigesada K, Wee HJ, Liu PP, Osato M, Ito Y

Blood · 2004 Apr 15 · PMID 15070703

Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms

Wee HJ, Huang G, Shigesada K, Ito Y

EMBO reports · 2002 Oct · PMID 12231506

Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

Huang G, Shigesada K, Ito K, Wee HJ, Yokomizo T, Ito Y

The EMBO journal · 2001 Feb 15 · PMID 11179217

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

Zhang YW, Yasui N, Ito K, Huang G, Fujii M, Hanai J, Nogami H, Ochi T, Miyazono K, Ito Y

Proceedings of the National Academy of Sciences of the United States of America · 2000 Sep 12 · PMID 10962029

Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2

Kohzaki H, Ito K, Huang G, Wee HJ, Murakami Y, Ito Y

Oncogene · 1999 Jul 15 · PMID 10435586

Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO

Ahn MY, Huang G, Bae SC, Wee HJ, Kim WY, Ito Y

Proceedings of the National Academy of Sciences of the United States of America · 1998 Feb 17 · PMID 9465099

A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells

Zhang YW, Bae SC, Huang G, Fu YX, Lu J, Ahn MY, Kanno Y, Kanno T, Ito Y

Molecular and cellular biology · 1997 Jul · PMID 9199349

A Critical Role of RUNX1 in Governing Megakaryocyte-Primed Hematopoietic Stem Cell Differentiation

Blood advances